• Bioimpedance technology fundamentals

Bioimpedance, also widely known as Electrical Bioimpedance (EBI),  is not a physiological variable, but a technique which allows the characterization of tissues and biological materials by means of their electrical behavior. In particular, bioimpedance represents the opposition of a biological material to the pass of a sinusoidal electrical current. Electrical current amplitudes used in EBI technology are so low that do not cause damage to biological tissues, which allows the technology to be incorporate to the healthcare of patients with different diseases and even in neonates.

Cells web

Bioimpedance is a complex number where the real part accounts for the resistance presented by the intra- and extracellular fluids of the biological tissue, and the imaginary part is a consequence of the temporal storage of electrical charges in the cellular membranes. Accordingly and depending on the composition, biological tissues behave as conductors or dielectrics and the corresponding composition can be known from their electrical characterization, i.e. bioimpedance.

Regarding to the frequency of the electrical current injected, Bioimpedance Analysis can be performed using an unique frequency value, which is usually 50 kHz. At this frequency, the electrical current flows through extra- and intracellular fluids. In contrast, Bioimpedance Spectroscopy carries out bioimpedance analyses sweeping the frequency of the current signal in a determined range and resolution.

Features such as innocuous, slight, relative inexpensive and easy-to-use, are aspects of the technique for the development of attractive bioimpedance-based applications for personal and professional uses.


  • BioBee wireless multichannel EBi measurement system

BioBee Technologies has carried out the design of a powerful wireless bioelectrical impedance multichannel development system based on the concept of Wireless Sensor Networks (WSN).

Bee web


The performance of the system provides the following features:

Flexibility: Any channel (node or 'bee') is an independent and remotely configurable bioelectrical impedance measurement instrument.

Scalability: Number of channels is completely open to satisfy the specific requirements of any application some of them unknown.

Simultaneity: Channels are capable of working at the same time or according to any timing sequence. 


chip web


Every node, which is mounted in a printed circuit board of very reduced dimensions powered from a single battery, includes an analog front-end, a microcontroller and a RF transceiver section. It performs as a high-performance EBI instrument able to carry out spectroscopy analysis or time-domain bioimpedance analysis.

The core is a powerful technological platform –hardware/software– implemented around proprietary IP high-performance CMOS analog front-end sections with wide frequency range (from 1kHz to 2MHz) and wide measurement range (impedance module from 1Ω to 3.5kΩ/ impedance phase from 1° to 90°).

A Graphical User Interface is used to define the WSN topology, individual channel functionality as well as wirelessly receive and analyze the measured results.


  • EBI applications 

Because of the flexibility and scability, the BioBee multichannel measurement system is a development tool open to all kind of EBI applications. It offers a lot of use possibilities some still unkown.